Bittercube was founded by Nicholas Kosevich and Ira Koplowitz in 2009. Based out of Milwaukee, WI, Bittercube's artisans literally create bitters by hand, peeling hundreds of pounds of citrus, weighing dozens of spices, and decorticating vanilla beans, among other time-consuming tasks. The process of batching the bitters is different for each style, taking anywhere from four to eight weeks depending on the variety.